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Diffuse-type gastric cancer: specific enhancement pattern on multiphasic contrast-enhanced computed tomography
Daisuke Tsurumaru1, Mitsutoshi Miyasaka2, Toshio Muraki2
1Departments of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Japan. tsuru-d@radiol.med.kyushu-u.ac.jp.
Multiphasic contrast-enhanced computed tomography gastrography (CECTG) reveals diffuse-type gastric cancers (DGCs) typically present a double-layered enhancement pattern in the arterial phase. This pattern transitions to a single layer with moderate enhancement in the delayed phase.
Area of Science:
- Radiology
- Gastroenterology
- Oncology
Background:
- Diffuse-type gastric cancer (DGC) presents diagnostic challenges.
- Multiphasic contrast-enhanced computed tomography gastrography (CECTG) is an imaging modality for gastric pathologies.
Purpose of the Study:
- To evaluate the enhancement patterns of DGCs using CECTG.
- To characterize the layered enhancement of DGCs in different CT phases.
Main Methods:
- 21 DGC patients underwent CECTG with gastric distension.
- CT images acquired in arterial (40s) and delayed (240s) phases.
- Radiologists analyzed layer and enhancement patterns, calculating CT attenuation values.
Main Results:
- Most DGCs exhibited a double-layered pattern in the arterial phase (inner: moderate, outer: mild enhancement).
- A single-layered pattern with moderate enhancement was observed in the delayed phase.
- Pathological analysis confirmed wall stratification in most cases.
Conclusions:
- CECTG demonstrates characteristic layered enhancement patterns in DGCs.
- The arterial phase shows a distinct double-layer, while the delayed phase shows a single layer.
- These findings aid in the radiological characterization of DGCs.
