Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimisation of Electrokinetic Extraction System: Colourimetric Determination of Copper (II) in Sand Using Polymer Inclusion Membrane.

Electrophoresis·2026
Same author

Microfluidic co-culture system for synaptically segregated neural networks to explore astrocyte-driven neural pathology.

Microsystems & nanoengineering·2026
Same author

Resolving the chemical space: a legacy of recording separation science and innovation in <i>Analyst</i>.

The Analyst·2026
Same author

Miniaturised electrophoretic analyser with integrated filter-free microfluidic sample treatment for monitoring of inorganic anions in water.

Analytica chimica acta·2025
Same author

Monitoring of Nonacog Beta Pegol: One-Stage Clotting Assay With Kaolin Reagent as a Practical Alternative to Chromogenic Methods.

Haemophilia : the official journal of the World Federation of Hemophilia·2025
Same author

Emicizumab prophylaxis in current haemophilia A care in the Czech Republic-data from the Czech National Haemophilia Programme Registry.

Research and practice in thrombosis and haemostasis·2025
Same journal

Structural Hairpin Anchoring-Mediated TtAgo Activity Regulation for Programmable Biosensing.

Analytical chemistry·2026
Same journal

Digital Revitalization of a Legacy Linear Ion Trap System.

Analytical chemistry·2026
Same journal

An Interface-Regulated Electrochemical Biosensing Platform Based on the Cascade Amplification of Primer Exchange Reaction and CRISPR/Cas12a for Noninvasive Bladder Cancer Diagnosis.

Analytical chemistry·2026
Same journal

Spatially Resolved Diffusion NMR for Structurally Heterogeneous Materials.

Analytical chemistry·2026
Same journal

Direct Whole-Blood Multiplexing of Small Molecules via a Micelle-Enhanced Chemiluminescent Paper Sensor with Mesoporous Silica Membrane.

Analytical chemistry·2026
Same journal

Modeling the Effects of Short-Range Randomness in Packed Sphere Beds.

Analytical chemistry·2026
See all related articles

Related Experiment Video

Updated: Mar 6, 2026

Three-Dimensionally Printed Microfluidic Cross-flow System for Ultrafiltration/Nanofiltration Membrane Performance Testing
10:19

Three-Dimensionally Printed Microfluidic Cross-flow System for Ultrafiltration/Nanofiltration Membrane Performance Testing

Published on: February 13, 2016

11.9K

Comparing Microfluidic Performance of Three-Dimensional (3D) Printing Platforms.

Niall P Macdonald1,2, Joan M Cabot1,2, Petr Smejkal2

  • 1ARC Centre of Excellence for Electromaterials Science, School of Physical Sciences, University of Tasmania , Sandy Bay, Hobart 7001, Tasmania, Australia.

Analytical Chemistry
|March 11, 2017
PubMed
Summary
This summary is machine-generated.

Three-dimensional (3D) printing technologies like FDM, Polyjet, and DLP-SLA offer distinct advantages for fabricating microfluidic devices. DLP-SLA provides the highest resolution and smoothest surfaces, ideal for precise flow control applications.

More Related Videos

Design of an Open-Source, Low-Cost Bioink and Food Melt Extrusion 3D Printer
08:01

Design of an Open-Source, Low-Cost Bioink and Food Melt Extrusion 3D Printer

Published on: March 2, 2020

10.6K
The Submerged Printing of Cells onto a Modified Surface Using a Continuous Flow Microspotter
08:29

The Submerged Printing of Cells onto a Modified Surface Using a Continuous Flow Microspotter

Published on: April 22, 2014

9.2K

Related Experiment Videos

Last Updated: Mar 6, 2026

Three-Dimensionally Printed Microfluidic Cross-flow System for Ultrafiltration/Nanofiltration Membrane Performance Testing
10:19

Three-Dimensionally Printed Microfluidic Cross-flow System for Ultrafiltration/Nanofiltration Membrane Performance Testing

Published on: February 13, 2016

11.9K
Design of an Open-Source, Low-Cost Bioink and Food Melt Extrusion 3D Printer
08:01

Design of an Open-Source, Low-Cost Bioink and Food Melt Extrusion 3D Printer

Published on: March 2, 2020

10.6K
The Submerged Printing of Cells onto a Modified Surface Using a Continuous Flow Microspotter
08:29

The Submerged Printing of Cells onto a Modified Surface Using a Continuous Flow Microspotter

Published on: April 22, 2014

9.2K

Area of Science:

  • Materials Science
  • Engineering
  • Biotechnology

Background:

  • Three-dimensional (3D) printing is a transformative technology for microfluidic device fabrication.
  • Fused Deposition Molding (FDM), Polyjet, and Digital Light Processing Stereolithography (DLP-SLA) are leading 3D printing methods in microfluidics.
  • Optimizing printer design is crucial for maximizing microfluidic device performance.

Purpose of the Study:

  • To experimentally compare FDM, Polyjet, and DLP-SLA for microfluidic device fabrication.
  • To evaluate printer performance based on feature size, accuracy, surface roughness, and mass manufacturing potential.
  • To assess the suitability of each technology for microfluidic applications by studying laminar flow and mixing characteristics.

Main Methods:

  • A Y-junction microfluidic device was designed and optimized for each of the three 3D printing technologies: FDM, Polyjet, and DLP-SLA.
  • Printer performance was assessed by measuring minimum feature size and surface roughness.
  • Laminar flow and fluid mixing efficiency were quantified to evaluate microfluidic functionality.

Main Results:

  • FDM produced features >500 μm with minimum sizes of 321 ± 5 μm and rough surfaces (10.97 μm), achieving rapid mixing (71% ± 12%).
  • Polyjet achieved smaller minimum channel sizes (205 ± 13 μm) with lower roughness (0.99 μm) but reduced mixing (27% ± 10%), suitable for cell culture or droplet generation.
  • DLP-SLA yielded the smallest minimum channel size (154 ± 10 μm) and smoothest surface (0.35 μm), with minimal mixing (8% ± 1%), ideal for precise flow control applications.

Conclusions:

  • Each 3D printing technology (FDM, Polyjet, DLP-SLA) presents unique strengths and limitations for microfluidic applications.
  • DLP-SLA is best suited for microfluidic applications demanding high precision and controlled flow.
  • Polyjet is advantageous for applications like cell culture and droplet generation, while FDM excels in fabricating micromixers.