α-pyrone derivatives from a marine actinomycete Nocardiopsis sp. YIM M13066
Xiao-Mei Zhang1, Ming-Wei Sun2, Hui Shi2
1b College of Basic Medicine , Yunnan University of Traditional Chinese Medicine , Kunming , China.
Abstract:
Five new α-pyrones namely nocapyrones O-S (2-6) and nocapyrone F (1) were isolated from a deep-sea sediment strain Nocardiopsis sp. YIM M13066. Their structures were elucidated by their NMR spectroscopic data, HR-ESI-MS and crystal X-ray diffraction. Their cytotoxic activities against H1299, HeLa, HL7702, MCF-7, PC3 and U251 cell lines were evaluated.
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