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Updated: Mar 6, 2026

Conventional BODIPY Conjugates for Live-Cell Super-Resolution Microscopy and Single-Molecule Tracking
Published on: June 8, 2020
PEGylated Perylenemonoimide-Dithienylethene for Super-Resolution Imaging of Liposomes
Jun-Xia Liu1, Bo Xin1, Chong Li1
1Wuhan National Laboratory for Optoelectronics, College of Optical and Electronic Information, Huazhong University of Science and Technology , Wuhan, Hubei 430074, China.
Abstract:
We have designed and synthesized an amphiphilic photoswitchable fluorophore, PEGylated perylenemonoimide-dithienylethene (PEG-PMI-DTE), which exhibits evident bistable photochromism, fluorescence switching, and fatigue resistance. The fine nanostructures of liposomes can be observed directly under super-resolution fluorescent microscopy by aid of the amphiphilic photoswitchable fluorophore as a staining agent, with an optical resolution of 30 nm.
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