Jove
Visualize
Contact Us

Related Concept Videos

Aging01:26

Aging

924
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
924
Interference and Decay01:16

Interference and Decay

549
Forgetting is a complex cognitive phenomenon influenced by several factors, among which interference and decay are particularly prominent. These processes explain why individuals often struggle to retrieve specific information from memory, leading to lapses in recall that can be observed in everyday situations.
Interference occurs when competing memories hinder the retrieval of particular information. It can be classified into two types: proactive and retroactive interference. Proactive...
549
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

1.0K
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
1.0K
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

4.0K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
4.0K
Long-term Depression01:03

Long-term Depression

3.5K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
3.5K
Long-term Depression01:05

Long-term Depression

33.6K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cell Growth and Division Shape mRNA-Protein Correlations.

bioRxiv : the preprint server for biology·2026
Same author

Extremal events dictate population growth rate inference.

PLoS computational biology·2026
Same author

Harnessing intuitive local evolution rules for physical learning.

Physical review. E·2026
Same author

Stochasticity in mammalian cell growth rates drives cell-to-cell variability independently of cell size and divisions.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Aging of amorphous materials under cyclic strain.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Design principles of transcription factors with intrinsically disordered regions.

eLife·2025
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Mar 6, 2026

Characterizing Multiscale Mechanical Properties of Brain Tissue Using Atomic Force Microscopy, Impact Indentation, and Rheometry
11:19

Characterizing Multiscale Mechanical Properties of Brain Tissue Using Atomic Force Microscopy, Impact Indentation, and Rheometry

Published on: September 6, 2016

13.1K

Nonmonotonic Aging and Memory Retention in Disordered Mechanical Systems.

Yoav Lahini1, Omer Gottesman1, Ariel Amir1

  • 1Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA.

Physical Review Letters
|March 11, 2017
PubMed
Summary

Crumpled sheets and elastic foams show nonmonotonic aging and memory effects, hallmarks of glassy dynamics. These disordered mechanical systems exhibit unique responses to compression changes, suggesting generic glassy behavior in athermal systems.

More Related Videos

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
14:57

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

Published on: March 23, 2011

95.4K
Age-dependent Dynamics of Locomotion in Caenorhabditis elegans: A Lyapunov Exponent Analysis
06:44

Age-dependent Dynamics of Locomotion in Caenorhabditis elegans: A Lyapunov Exponent Analysis

Published on: September 23, 2025

651

Related Experiment Videos

Last Updated: Mar 6, 2026

Characterizing Multiscale Mechanical Properties of Brain Tissue Using Atomic Force Microscopy, Impact Indentation, and Rheometry
11:19

Characterizing Multiscale Mechanical Properties of Brain Tissue Using Atomic Force Microscopy, Impact Indentation, and Rheometry

Published on: September 6, 2016

13.1K
Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
14:57

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

Published on: March 23, 2011

95.4K
Age-dependent Dynamics of Locomotion in Caenorhabditis elegans: A Lyapunov Exponent Analysis
06:44

Age-dependent Dynamics of Locomotion in Caenorhabditis elegans: A Lyapunov Exponent Analysis

Published on: September 23, 2025

651

Area of Science:

  • Physics
  • Materials Science
  • Soft Matter Physics

Background:

  • Glassy dynamics are typically characterized by aging and memory effects.
  • Disordered mechanical systems like crumpled sheets and elastic foams often exhibit complex relaxation behaviors.

Purpose of the Study:

  • To investigate nonmonotonic aging and memory effects in crumpled thin sheets and elastic foams.
  • To determine if these systems display genuine glassy behavior.

Main Methods:

  • Applying fixed compression to disordered mechanical systems.
  • Introducing partial reduction in compression after a waiting time.
  • Observing and measuring the normal force response over time.
  • Analyzing the relationship between peak time and waiting time.

Main Results:

  • Both systems showed monotonic, nonexponential relaxation under fixed compression.
  • Upon partial compression reduction, a nonmonotonic response was observed: initial force increase followed by relaxation.
  • The peak time for force increase scaled linearly with the waiting time, indicating memory effects.
  • Results align with theoretical models for glassy systems.

Conclusions:

  • Disordered mechanical systems can exhibit nonmonotonic aging and memory effects, characteristic of glassy dynamics.
  • The observed phenomena suggest that athermal systems can display genuine glassy behavior.
  • The findings support the universality of glassy dynamics across different material types.