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Updated: Mar 6, 2026
09:04
Isolation And Dendritic Cell-Uptake of Small Extracellular Vesicles from Echinococcus granulosus
Published on: March 28, 2025
823
[Molecular characterization of Echinococcus granulosus isolates obtained from different hosts]
Emrah Erdoğan1, Bora Özkan, Fatih Mutlu
1Erciyes University Medical Faculty, Department of Medical Parasitology, Kayseri, Turkey. emrah@erciyes.edu.tr.
Mikrobiyoloji Bulteni
|March 12, 2017
Summary
This study identified Echinococcus granulosus strains in Turkey using molecular methods. All isolates were confirmed as E. granulosus sensu stricto (G1), crucial for controlling this parasitic disease.
Area of Science:
- Veterinary Parasitology
- Molecular Biology
- Public Health
Background:
- Echinococcus granulosus causes Cystic Echinococcosis (CE), a significant global health and economic issue.
- CE affects intermediate hosts like livestock and humans, with adult parasites in canines.
- Genetic diversity among E. granulosus strains complicates control efforts.
Purpose of the Study:
- To molecularly characterize E. granulosus strains from various intermediate hosts in Turkey.
- To provide data for improved parasite control, diagnosis, and treatment strategies.
Main Methods:
- Collected cyst material from human, cattle, sheep, and goat hosts across Turkey.
- Isolated genomic DNA from protoscoleces and performed PCR using COX-1 gene primers.
- Analyzed DNA sequences phylogenetically using MEGA and BLAST software.
Main Results:
- All analyzed isolates were identified as E. granulosus sensu stricto (G1).
- Molecular analysis confirmed a specific strain prevalent in the studied intermediate hosts.
Conclusions:
- The findings confirm the predominance of E. granulosus sensu stricto (G1) in Turkey.
- This data is vital for developing targeted control, eradication, and treatment strategies for CE.
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