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Published on: November 1, 2017
Liposomal Co-Encapsulation of Two Novel Europium Complexes and Doxorubicin: Fluorescence Study
Valeriya M Trusova1,2, Todor Deligeorgiev3, Galyna Gorbenko4
1Department of Nuclear and Medical Physics, V.N. Karazin Kharkov National University, 4 Svobody Sq, Kharkov, 61072, Ukraine. valeriya.m.trusova@gmail.com.
Abstract:
The present study was undertaken to design the novel liposomal drug formulation containing doxorubicin and europium coordination complexes. It was shown that co-encapsulation of the drugs facilitates the partitioning and permeation of lanthanides into the lipid bilayer. The obtained results suggest that new drug platform may have potential application in the design of novel antitumor agents.
