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Design development and evaluation of triphala tablets.
Journal of Complementary & Integrative Medicine
|March 12, 2017
Summary
This study successfully developed reproducible Triphala tablets using direct compression. The optimized tablets met all pharmacopoeial evaluation standards, ensuring quality for this ancient herbal remedy.
Area of Science:
- Ayurvedic Medicine
- Pharmaceutical Sciences
- Herbal Drug Formulation
Background:
- Triphala, a traditional Ayurvedic formulation, combines Amla, Bahera, and Haritaki.
- It is widely available as a powder (churna) and has been used for centuries.
- Standardizing herbal formulations like Triphala into dosage forms is crucial for consistent therapeutic effects.
Purpose of the Study:
- To develop reproducible batches of Triphala tablets.
- To evaluate the optimized Triphala tablet formulation.
- To ensure the quality and consistency of Triphala in a tablet dosage form.
Main Methods:
- Direct compression method was utilized for tablet preparation.
- Various directly compressible excipients (MicroceLac, Ludipress, Ludiflash) were tested.
- High-Performance Liquid Chromatography (HPLC) with gallic acid as a marker was used for herb authentication.
Main Results:
- Reproducible batches of 600 mg Triphala tablets were successfully formulated.
- All formulated tablets met the pharmacopoeial standards for evaluation.
- HPLC confirmed the authenticity of the herbs in the formulation.
Conclusions:
- Direct compression is a viable method for producing quality Triphala tablets.
- The developed Triphala tablets are stable and meet required quality parameters.
- This formulation provides a standardized and convenient dosage form for Triphala.
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