IgG4-Related Tubulointerstitial Nephritis

Pingchuan Zhang1, Lynn D Cornell1

  • 1Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.

Summary

Immunoglobulin G4 (IgG4)-related disease can affect any organ, with IgG4-related tubulointerstitial nephritis (IgG4-TIN) being the most common kidney manifestation. While often responsive to steroids, IgG4-TIN has a high relapse rate after stopping treatment.

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