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Electrospun starch nanofibers: Recent advances, challenges, and strategies for potential pharmaceutical applications
Guodong Liu1, Zhengbiao Gu1, Yan Hong1
1The State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, Jiangsu Province, PR China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, Jiangsu Province, PR China; Collaborative Innovation Center for Food Safety and Quality Control, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, Jiangsu Province, PR China.
Abstract:
Electrospun starch nanofibers have high porosity, extremely high specific surface area, and biocompatible, biodegradable, and bioabsorbable properties. As a result, starch nanofibers have great potential in pharmaceutical applications, including drug delivery, wound dressing, and tissue engineering. Here, we summarize and review the recent developments in the synthesis of electrospun starch fibers from common starch, modified starch, and hybrids with other polymers. Moreover, the challenges and strategies for the fabrication and application of starch fibers in pharmaceutical applications are presented.
