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Knee Joint

Knee Joint

The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...

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Related Experiment Video

Updated: Mar 6, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

Published on: July 22, 2021

Arthrofibrosis Associated With Total Knee Arthroplasty.

Victor A Cheuy¹, Jared R H Foran², Roger J Paxton¹

¹Physical Therapy Program, Department of Physical Medicine and Rehabilitation, University of Colorado, Aurora, Colorado.

The Journal of Arthroplasty

|March 14, 2017

Summary

Arthrofibrosis after total knee arthroplasty (TKA) causes stiffness and functional loss. Early, tailored physiotherapy is key, but invasive treatments may be needed for severe cases.

Keywords:

arthrofibrosis arthroplasty range of motion stiffness total knee

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Area of Science:

Orthopedics
Rehabilitation Medicine
Biomedical Engineering

Background:

Arthrofibrosis is a significant complication following total knee arthroplasty (TKA), leading to functional deficits.
It is a primary cause of TKA failure and hospital readmissions, with increasing prevalence.
Excessive scar tissue formation impairs wound healing and causes joint stiffness.

Purpose of the Study:

To review the etiology, economic impact, and treatment strategies for arthrofibrosis after TKA.
To identify future research directions for managing this complication.

Main Methods:

A narrative literature review was conducted.
The review examined the causes, costs, treatments, and research gaps related to TKA arthrofibrosis.

Main Results:

Supervised physiotherapy is the primary treatment, with adjuncts like splinting potentially beneficial.
Rehabilitation effectiveness hinges on appropriate timing, intensity, and patient-specific progression.
Invasive options like manipulation under anesthesia or revision surgery can improve motion but carry risks and costs.

Conclusions:

Arthrofibrosis is complex and challenging to treat without early, individualized rehabilitation.
Understanding risk factors and intervention effectiveness is crucial for restoring patient mobility and function.