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Updated: Mar 6, 2026

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Published on: November 27, 2016
Malabsorption Secondary to Gout-Induced Amyloidosis
Ali Azzam1, Renuka Balasubramaniam1, Shahram Safa1
1Department of Gastroenterology, Logan Hospital, Queensland, Australia.
Abstract:
Many chronic inflammatory conditions can lead to systemic amyloidosis. However, secondary amyloidosis has rarely been associated with gout, and the literature reports only a handful of cases, all presenting with renal disease. We report a patient with a history of poorly controlled gout who presented with malabsorption. Endoscopic biopsies confirmed a diagnosis of small intestinal amyloidosis. This was believed to be a consequence of gout. Interestingly, renal involvement was subclinical. Our case raises awareness of this rare association and highlights the importance of considering a diagnosis of amyloidosis in patients who present with the combination of gout and gastrointestinal symptoms.
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