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Related Concept Videos

Clinical Trials01:16

Clinical Trials

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Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
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Sampling Methods: Overview01:06

Sampling Methods: Overview

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A sample refers to a smaller subset representative of a larger population. In analytical chemistry, studying or analyzing an entire population is often impractical or impossible. Therefore, samples are used to draw inferences and generalize the whole population. The sampling method selects individuals or items from a population to create a sample. Standard sampling methods include random, judgemental, systematic, stratified, and cluster sampling. 
In analytical chemistry, the choice of...
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Random Sampling Method01:09

Random Sampling Method

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Sampling is a technique to select a portion (or subset) of the larger population and study that portion (the sample) to gain information about the population. Data are the result of sampling from a population. The sampling method ensures that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest. Among the various sampling methods used by...
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Study Designs in Epidemiology01:20

Study Designs in Epidemiology

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Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
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Surveys02:16

Surveys

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Often, psychologists develop surveys as a means of gathering data. Surveys are lists of questions to be answered by research participants, and can be delivered as paper-and-pencil questionnaires, administered electronically, or conducted verbally. Generally, the survey itself can be completed in a short time, and the ease of administering a survey makes it easy to collect data from a large number of people.
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Cluster Sampling Method01:20

Cluster Sampling Method

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Appropriate sampling methods ensure that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest.
To choose a cluster sample, divide the population into clusters (groups) and then randomly select some of the clusters. All the members from these clusters are in the cluster sample. For example, if you randomly sample four departments from your...
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Related Experiment Video

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A Method to Test the Efficacy of Handwashing for the Removal of Emerging Infectious Pathogens
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Sampling methods in Clinical Research; an Educational Review.

Mohamed Elfil1, Ahmed Negida2

  • 1Faculty of Medicine, Alexandria University, Egypt.

Emergency (Tehran, Iran)
|March 14, 2017
PubMed
Summary

Understanding clinical research sampling methods is crucial for ensuring study findings are applicable to broader patient populations. This article explains various sampling techniques to improve the generalizability of clinical research.

Keywords:
Research designeducationevidence-based medicinepopulation surveillancesampling studies

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Area of Science:

  • Clinical Research Methodology
  • Biostatistics
  • Epidemiology

Background:

  • Clinical research validity relies on generalizability to diverse patient groups.
  • Sampling methods are a key determinant of research findings' external validity.
  • Methodological rigor in participant selection is essential for reliable clinical data.

Purpose of the Study:

  • To educate readers on diverse sampling methods used in clinical research.
  • To highlight the impact of sampling techniques on the generalizability of study outcomes.
  • To provide a foundational understanding of participant selection in clinical trials.

Main Methods:

  • This article provides an educational overview of sampling methodologies.
  • It discusses various techniques for selecting participants in clinical studies.
  • Key concepts of internal and external validity are explained in relation to sampling.

Main Results:

  • Different sampling methods possess unique strengths and weaknesses.
  • The choice of sampling method directly impacts the generalizability of results.
  • Appropriate sampling enhances the external validity of clinical research.

Conclusions:

  • Selecting the correct sampling method is critical for robust clinical research.
  • Understanding sampling techniques improves the interpretation and application of research findings.
  • This educational piece serves as a guide to sampling in clinical research.