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Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles
Published on: December 1, 2016
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Curcumin Nanotechnologies and Its Anticancer Activity
Parasuraman Aiya Subramani1,2, Kalpana Panati3, Venkata Ramireddy Narala1
1a Department of Zoology , Yogi Vemana University , Kadapa , India.
Nutrition and Cancer
|March 14, 2017
Summary
Curcumin shows anticancer promise, but poor bioavailability limits clinical success. Nanoparticle drug carriers significantly enhance curcumin
Area of Science:
- Oncology
- Nanotechnology
- Pharmacology
Background:
- Cancer remains a leading global cause of mortality.
- Curcumin exhibits potent in vitro anticancer properties.
- Poor bioavailability hinders clinical efficacy of curcumin treatments.
Purpose of the Study:
- To review nanotechnology-based strategies for enhancing curcumin bioavailability.
- To explore diverse nanoparticle formulations for curcumin delivery.
- To discuss future research directions for curcumin nanoparticles.
Main Methods:
- Review of existing literature on curcumin nanoparticles.
- Categorization of nanotechnologies based on complexity and function.
- Analysis of curcumin-metal complexes and thermoresponsive nanoparticles.
Main Results:
- Nanoparticle drug carriers effectively improve curcumin bioavailability.
- Curcumin-metal complexes represent a simple yet effective nanoparticle form.
- Advanced systems like thermoresponsive nanoparticles offer controlled release mechanisms.
Conclusions:
- Nanotechnology offers viable solutions to overcome curcumin's bioavailability challenges.
- Development of novel curcumin nanoparticles is crucial for clinical translation.
- Further research is needed to optimize potent curcumin nanoparticle formulations.
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