Lower-Extremity Pseudomyogenic Hemangioendothelioma on Bone Scintigraphy and PET/CT
Simone Krebs1, Serena Monti, Natasha Lewis
1From the *Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY; †IRCCS SDN, Naples, Italy; ‡Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY; §Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT; and ∥Carson GrahamSecondary School, North Vancouver, British Columbia, Canada.
Abstract:
An otherwise healthy 33-year-old man presents with new pain involving the right leg. Radiographs of the femur showed scattered lucent lesions. An MRI of the knee demonstrated nonspecific cortical-based lesions. Biopsy confirmed pseudomyogenic hemangioendothelioma. MDP bone scan and F-FDG PET/CT were obtained to evaluate for extent of disease demonstrating disease limited to the bone of the right leg. Interestingly, the FDG and MDP uptake and CT appearance of the disease were not entirely concordant, with some lesions being lytic on CT and associated with FDG and MDP uptake, other lesions being CT silent and either MDP or FDG avid.
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