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FDG PET/CT in Pediatric Neurolymphomatosis
Carole de Vaugelade1, Henri de Clermont-Gallerande, Marie Meyer
1From the *Service de Médecine Nucléaire, Pellegrin, CHU de Bordeaux, Bordeaux; †Service de Pédiatrie Médicale, Hématologie Pédiatrique, Pellegrin, CHU de Bordeaux, Bordeaux; ‡Service de Radiologie et d'Imagerie Anténatale, de l'Enfant et de la Femme, Pellegrin, CHU de Bordeaux; §INCIA, UMR CNRS 5287, Bordeaux; and ∥Université de Bordeaux, Bordeaux, France.
Abstract:
An 8-year-old girl presented with back and leg pain and left arm and leg paresis. Lumbar puncture was suggestive of lymphocytic meningitis without identified organism. A second lumbar puncture demonstrated a large number of lymphoid B cells, with positive immunohistochemical staining for CD20 and CD25, proving the diagnosis of neurolymphomatosis. Brain and spine MRI demonstrated involvement of cervical and lumbosacral nerve roots. FDG PET/CT showed multiple bone metastases in addition to nerve involvement. Postchemotherapy FDG PET/CT demonstrated complete metabolic response.
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Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...

