Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Working Memory01:24

Working Memory

1.1K
Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...
1.1K
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

1.3K
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Molecular, cellular and network mapping of brain structural deviations in patients with Post-COVID19 syndrome.

Brain, behavior, & immunity - health·2026
Same author

The intrinsic cortical geometry of reading.

bioRxiv : the preprint server for biology·2026
Same author

The association between autistic traits and trajectories of anxiety in middle-aged and older adults: an 8-year growth mixture model analysis.

Nature. Mental health·2026
Same author

Cortical synchrony is reduced in Alzheimer's disease and relates to arousal state.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Brain dynamics of attentional, default-mode and limbic networks are disrupted at rest in post-COVID-19 syndrome.

Brain, behavior, & immunity - health·2026
Same author

Reducing Motion Artifact in High Resolution 7 T MRI Using the Magnetic Resonance Minimal Motion ("MR-MinMo") Head Stabilization Device.

Magnetic resonance in medicine·2026

Related Experiment Video

Updated: Mar 6, 2026

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
09:26

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication

Published on: February 6, 2019

22.3K

Externally induced frontoparietal synchronization modulates network dynamics and enhances working memory performance.

Ines R Violante1,2, Lucia M Li1, David W Carmichael3

  • 1The Computational, Cognitive and Clinical Neuroimaging Laboratory, Department of Medicine, Imperial College London, London, United Kingdom.

Elife
|March 15, 2017
PubMed
Summary
This summary is machine-generated.

This study shows that externally synchronized brain oscillations improve working memory (WM) performance, especially under high cognitive load. The findings link brain synchronization patterns to behavioral outcomes in demanding WM tasks.

Keywords:
Working memorybrain networksbrain stimulationhumanneuroscienceoscillationssynchronizationtACS

More Related Videos

Inter-Brain Synchrony in Open-Ended Collaborative Learning: An fNIRS-Hyperscanning Study
04:44

Inter-Brain Synchrony in Open-Ended Collaborative Learning: An fNIRS-Hyperscanning Study

Published on: July 21, 2021

5.1K
Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice
07:03

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

Published on: July 31, 2019

7.3K

Related Experiment Videos

Last Updated: Mar 6, 2026

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
09:26

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication

Published on: February 6, 2019

22.3K
Inter-Brain Synchrony in Open-Ended Collaborative Learning: An fNIRS-Hyperscanning Study
04:44

Inter-Brain Synchrony in Open-Ended Collaborative Learning: An fNIRS-Hyperscanning Study

Published on: July 21, 2021

5.1K
Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice
07:03

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

Published on: July 31, 2019

7.3K

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Brain Imaging

Background:

  • Working memory (WM) relies on large-scale brain network interactions.
  • Oscillatory activity synchronization may facilitate long-range neural coordination for WM.
  • Limited causal evidence exists on how oscillations influence human WM network dynamics and behavior.

Purpose of the Study:

  • To investigate the causal role of oscillatory activity in supporting human working memory.
  • To explore how exogenous modulation of brain oscillations affects WM performance and network dynamics.
  • To determine the influence of transcranial alternating current stimulation (tACS) phase on WM network activity and behavior.

Main Methods:

  • Applied transcranial alternating current stimulation (tACS) to modulate oscillatory activity in a right frontoparietal network.
  • Measured behavioral performance during a verbal working memory task under varying cognitive demands.
  • Collected simultaneous functional magnetic resonance imaging (fMRI) data to assess brain activity and functional connectivity.

Main Results:

  • Exogenously induced oscillatory synchronization via tACS enhanced working memory performance during high cognitive load.
  • tACS effects on brain activity were dependent on the relative phase between stimulation and internal cognitive states.
  • Synchronous tACS increased parietal activity and altered frontoparietal functional connectivity, correlating with improved behavioral performance.

Conclusions:

  • Demonstrates a causal link between large-scale brain synchronization and behavioral performance in demanding working memory tasks.
  • Highlights the importance of the relative phase of neural oscillations for effective information flow within WM networks.
  • Provides evidence for tACS as a tool to modulate brain network dynamics and enhance cognitive functions like working memory.