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HIV-HCV Coinfection.

Amrita Sethi1, Richard K Sterling1

  • 1Dr. Sethi is a Senior Fellow in Hepatology and Dr. Sterling is Associate Professor of Medicine and Director of the HIV-Liver Disease Clinic, both in the Division of Gastroenterology, Hepatology, and Nutrition of the Virginia Commonwealth University Health System, Richmond, Va.

Gastroenterology & Hepatology
|March 15, 2017
PubMed
Summary
This summary is machine-generated.

Human immunodeficiency virus (HIV) and hepatitis C virus (HCV) coinfection is common. Management is crucial as liver-related mortality has increased in coinfected patients despite advances in HIV treatment.

Keywords:
HCVHIVHIV-HCV coinfectionliver biopsy

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Area of Science:

  • Infectious Diseases
  • Hepatology
  • Public Health

Background:

  • Human immunodeficiency virus (HIV) and hepatitis C virus (HCV) are significant global health issues.
  • Shared transmission routes lead to frequent coinfection, posing complex clinical challenges.
  • Advancements in antiretroviral therapy have reduced HIV mortality but increased the relative burden of liver disease in coinfected individuals.

Purpose of the Study:

  • To review the current epidemiology of HIV/HCV coinfection.
  • To outline essential evaluation strategies for coinfected patients.
  • To present key principles for effective management of this population.

Main Methods:

  • Literature review focusing on epidemiology, evaluation, and management of HIV/HCV coinfection.
  • Synthesis of current research and clinical guidelines.
  • Identification of critical management principles.

Main Results:

  • HIV/HCV coinfection remains a prevalent global health concern.
  • Liver-related mortality has notably increased in coinfected patients post-antiretroviral therapy introduction.
  • Effective management requires a comprehensive approach addressing both viral infections.

Conclusions:

  • Successful management of HIV/HCV coinfected patients necessitates understanding their epidemiology and evaluation.
  • Adherence to established management principles is vital for improving outcomes.
  • Further research and clinical attention are warranted for this challenging patient group.