Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

576
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
576
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

569
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
569
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

431
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
431
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

1.0K
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
1.0K
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

465
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
465
Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists01:23

Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists

558
Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
558

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction to: 2025 ACC/AHA/ASE/ASNC/SCCT/SCMR Advanced Training Statement on Advanced Cardiovascular Imaging: A Report of the ACC Competency Management Committee.

Circulation. Cardiovascular imaging·2026
Same author

Cerebral Microembolization Generated by Percutaneously Implanted Microaxial Left Ventricular Assist Device.

Journal of cardiothoracic and vascular anesthesia·2026
Same author

Feasibility of optical coherence tomography for localizing and quantifying paclitaxel deposition after drug-coated balloon angioplasty.

International journal of cardiology·2026
Same author

Retrograde type A aortic dissection following endovascular arch repair: what do clinicians need to be aware of?

Expert review of cardiovascular therapy·2026
Same author

Reply.

Journal of vascular surgery·2026
Same author

Endovascular aortic retrieval of migrated iliac stent.

Journal of vascular surgery cases and innovative techniques·2026
Same journal

Embolization Followed by Self-Repositioning of a CardioMEMSâ„¢ Wireless Pulmonary Artery Hemodynamic Monitoring Sensor Device.

Methodist DeBakey cardiovascular journal·2026
Same journal

Anomalous Origin of the Vertebral Artery from Thyrocervical Trunk: A Rare Anatomical Variant.

Methodist DeBakey cardiovascular journal·2026
Same journal

Intra-atrial Baffling of an Infradiaphragmatic Scimitar Vein without Circulatory Arrest.

Methodist DeBakey cardiovascular journal·2026
Same journal

Value of Myocardial Strain in Assessing Cardiac Masses: A Case Report.

Methodist DeBakey cardiovascular journal·2026
Same journal

Transient Cortical Blindness and Hemi-Spatial Neglect Following Watchman Device Implantation.

Methodist DeBakey cardiovascular journal·2026
Same journal

Hemodynamics of Pericardial Constriction: Role of Echocardiography and Cardiac Catheterization.

Methodist DeBakey cardiovascular journal·2026
See all related articles

Related Experiment Video

Updated: Mar 6, 2026

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
06:59

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis

Published on: August 26, 2025

675

Interventional Therapy for Pulmonary Embolism.

Alan B Lumsden1, Erik Suarez1

  • 1Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas.

Methodist Debakey Cardiovascular Journal
|March 15, 2017
PubMed
Summary
This summary is machine-generated.

Pulmonary embolism (PE) treatment is evolving with hybrid approaches combining surgery and catheter interventions. New diagnostic tools and techniques like pulmonary angioplasty improve acute PE management and thrombus removal.

Keywords:
AngioVac systemopen surgical thrombectomypulmonary embolismultrasound-assisted catheter-directed thrombolysis

More Related Videos

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

920
Myocardial Infarction by Percutaneous Embolization Coil Deployment in a Swine Model
05:52

Myocardial Infarction by Percutaneous Embolization Coil Deployment in a Swine Model

Published on: November 4, 2021

3.4K

Related Experiment Videos

Last Updated: Mar 6, 2026

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
06:59

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis

Published on: August 26, 2025

675
A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

920
Myocardial Infarction by Percutaneous Embolization Coil Deployment in a Swine Model
05:52

Myocardial Infarction by Percutaneous Embolization Coil Deployment in a Swine Model

Published on: November 4, 2021

3.4K

Area of Science:

  • Cardiology
  • Interventional Radiology
  • Thoracic Surgery

Background:

  • Pulmonary embolism (PE) presents with diverse symptoms and comorbidities, necessitating timely diagnosis and treatment.
  • Traditional surgical thrombectomy is now reconsidered for select patients, with a focus on early intervention.
  • Catheter-based interventions, often combined with surgical elements, are gaining traction for PE management.

Purpose of the Study:

  • To review current therapeutic options for pulmonary embolism at Houston Methodist DeBakey Heart & Vascular Center.
  • To describe the development of a novel pulmonary angioplasty procedure for acute PE.
  • To highlight advancements in diagnosing and treating life-threatening PE.

Main Methods:

  • Utilizing hybrid operating rooms for on-table contrast-enhanced cone-beam CT scans for PE diagnosis.
  • Employing large-bore thrombectomy devices via sternotomy or subxiphoid approaches.
  • Developing and implementing a pulmonary angioplasty technique for selective thrombus removal.

Main Results:

  • Improved diagnostic capabilities enable expedited diagnosis and treatment of massive PE.
  • Hybrid approaches allow for precise, image-guided interventions.
  • The novel pulmonary angioplasty procedure facilitates selective thrombus removal in acute PE.

Conclusions:

  • Careful patient selection and early intervention are key in managing PE.
  • Hybrid rooms and advanced imaging enhance therapeutic precision for PE.
  • The described pulmonary angioplasty procedure offers a promising advancement in acute PE treatment.