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[Assessment of Relationship Between Cardiovascular Risk and Risk of Development of Diabetes Mellitus]
M N Mamedov1,2, V N Korneeva1,2, O Sh Oynotkinova1,2
1National Research Center for Preventive Medicine, Moscow, Russia.
Insights
Cardiovascular risk (CVR) is strongly linked to diabetes mellitus (DM) risk in working-age men. High DM risk significantly correlates with very high CVR, particularly with metabolic factors.
Area of Science:
- Cardiology
- Endocrinology
- Preventive Medicine
Background:
- Cardiovascular disease (CVD) and diabetes mellitus (DM) are leading causes of morbidity and mortality.
- Identifying individuals at high risk for both conditions is crucial for preventive strategies.
Purpose of the Study:
- To investigate the relationship between cardiovascular risk (CVR) and the risk of developing diabetes mellitus (DM).
- To analyze this interrelationship in a cohort of working-age men.
Main Methods:
- A cohort of 300 men aged 40-59 years with at least one risk factor was studied.
- Cardiovascular risk (CVR) was assessed using the European SCORE scale.
- Diabetes mellitus (DM) risk was estimated using The Finnish Diabetes Risk Score (FINDRISC).
Main Results:
- Men with high and very high DM risk exhibited the highest rates of very high CVR.
- A significant correlation was observed between DM risk and metabolic factors, arterial pressure, lipid profile, age, and sedentary lifestyle.
- No significant correlation was found between DM risk and left ventricular hypertrophy, smoking, or tachycardia.
Conclusions:
- A strong association exists between elevated diabetes mellitus risk and high cardiovascular risk in middle-aged men.
- Metabolic risk factors play a key role in the interplay between DM and CVR.
- These findings highlight the importance of integrated risk assessment for both conditions.
Aim:
to analyze interrelationship between cardiovascular risk (CVR) and risk of development of diabetes mellitus (DM) in a cohort of working age men.
Material And Methods:
We enrolled in this study 300 men aged 40-59 years with more or equal 1 risk factors. Examination included questionnaire, standard clinical, instrumental, and laboratory studies. CVR and risk of developing DM was estimated using European SCORE scale and The Finnish Diabetes Risk Score (FINDRISC) respectively.
Results:
In a group of men with low risk of DM prevailed subjects with low-moderate CVR; every fourth person in this group had high and every tenth - very high CVR. In the group of men with moderately high risk of DM every second subject had high and every third - very high CVR. In the group of men with high and very high risk of DM every second subject had very high CVR. DM risk correlated most closely with metabolic risk factors. Less pronounced but significant correlation existed between levels of DM and CVR risk and parameters of arterial pressure, lipid spectrum, age, and sedentary lifestyle. There was no significant correlation between DM risk and left ventricular hypertrophy, smoking, and tachycardia.
Conclusion:
Highest rate of very high CVR was revealed among men with high and very high risk of DM, while rate of high CVR in groups with moderately high and high risk of DM appeared to be comparable.
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