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[Cardio-hepatic Syndrome in Heart Failure: Prevalence, Pathogenesis and Prognostic Significance]

Zh D Kobalava1, S V Villevalde1, A E Soloveva1

  • 1Peoples Friendship University, Moscow, Russia.

Kardiologiia
|March 15, 2017
PubMed

Insights

Cardio-hepatic syndrome (CHS) links heart and liver issues. This review details CHS mechanisms, prevalence, and its impact on patients with heart failure (HF), highlighting liver dysfunction in cardiac conditions.

Area of Science:

  • Cardiology
  • Hepatology
  • Organ Interactions

Background:

  • Recent research highlights the interplay between the heart and liver.
  • Cardio-hepatic syndrome (CHS) is defined as concurrent liver dysfunction and cardiac pathology.

Purpose of the Study:

  • To elucidate the mechanisms and characteristics of CHS in acute and chronic heart failure (HF).
  • To review prevalence, associations, and prognostic significance of cardiogenic liver dysfunction in HF patients.

Main Methods:

  • Review of mechanisms and characteristics of CHS.
  • Analysis of data from large clinical studies and registries on HF patients.

Main Results:

  • Detailed presentation of CHS mechanisms in acute and chronic HF.
  • Inclusion of prevalence, associations, and prognostic data from clinical studies and registries.

Conclusions:

  • CHS is a significant clinical entity in heart failure.
  • Understanding CHS is crucial for managing patients with co-existing cardiac and liver conditions.

Keywords:
cardiohepatic syndromeheart failureorgan interactions

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