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Sex differences in gout characteristics: tailoring care for women and men
Leslie R Harrold1, Carol J Etzel2,3, Allan Gibofsky4
1Department of Medicine and Orthopedics, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA. leslie.harrold@umassmed.edu.
Background:
To characterize the differences between women and men with gout.
Methods:
We analyzed a US national cohort of gout patients cared for by rheumatologists.
Results:
Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater burden of comorbid conditions (p < 0.001 for hypertension, diabetes, renal disease and obesity). Risk factors for gout differed with women more often taking diuretics (p < 0.001), while men more frequently had dietary triggers (p < 0.05).
Conclusions:
The profiles of women and men with gout are markedly different, suggesting a need to tailor treatment recommendations.
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