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Related Experiment Video

Updated: Mar 6, 2026

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Selected Endoscopic Gastric Devices for Obesity.

Kartik Sampath1, Richard I Rothstein1

  • 1Section of Gastroenterology and Hepatology, Department of Medicine, Dartmouth-Hitchcock Medical Center, Geisel School of Medicine at Dartmouth, One Medical Center Drive, Lebanon, NH 03756, USA.

Gastrointestinal Endoscopy Clinics of North America
|March 16, 2017
PubMed
Summary

New bariatric endoscopic devices targeting the stomach are in development to promote weight loss. These devices aim to alter gastric physiology, influencing volume, emptying, and satiety for effective obesity management.

Keywords:
Bariatric endoscopyDevicesObesityStomachTherapeutic endoscopy

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Area of Science:

  • Gastroenterology and Bariatric Medicine

Background:

  • Obesity is a complex global health issue requiring innovative treatment strategies.
  • Bariatric interventions are crucial for managing severe obesity and its comorbidities.
  • Endoscopic devices offer less invasive alternatives to traditional bariatric surgery.

Purpose of the Study:

  • To review current and emerging endoscopic devices targeting the stomach for weight loss.
  • To discuss the mechanisms by which these devices alter gastric physiology and promote satiety.
  • To highlight the potential of these novel devices in bariatric therapy.

Main Methods:

  • Review of current literature on stomach-targeting bariatric endoscopic devices.
  • Analysis of device mechanisms affecting gastric volume, emptying, compliance, and neurohormonal signaling.
  • Discussion of devices in various stages of clinical development.

Main Results:

  • Several stomach-targeting endoscopic devices are in development, distinct from approved intragastric balloons or small bowel devices.
  • These devices aim to modify gastric function to induce weight loss and improve satiety.
  • Further research is needed to establish the safety and efficacy of these emerging technologies.

Conclusions:

  • Stomach-targeting endoscopic devices represent a promising frontier in bariatric therapy.
  • These devices offer a potentially less invasive approach to obesity management by directly influencing gastric physiology.
  • Ongoing research and clinical trials are essential to validate their long-term safety and effectiveness.