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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Acetaminophen use and asthma in children.

Teeranai Sakulchit, Ran D Goldman

    Canadian Family Physician Medecin De Famille Canadien
    |March 16, 2017
    PubMed
    Summary
    This summary is machine-generated.

    Acetaminophen is likely safe for a single dose in children with asthma. Regular use does not appear to worsen asthma symptoms more than ibuprofen.

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    Area of Science:

    • Pediatric Medicine
    • Pulmonology
    • Pharmacology

    Background:

    • Acetaminophen (APAP) is a common antipyretic and analgesic.
    • Observational studies suggest a correlation between APAP use and asthma development.
    • Confounding factors in existing research complicate definitive conclusions.

    Purpose of the Study:

    • To evaluate the safety of acetaminophen in children with a history of asthma.
    • To determine if acetaminophen exacerbates asthma symptoms.

    Main Methods:

    • Review of existing literature on acetaminophen use and asthma.
    • Analysis of confounding factors in previous study designs.
    • Consideration of prospective controlled trial limitations.

    Main Results:

    • A single dose of acetaminophen is likely safe for children with known asthma.
    • No evidence suggests acetaminophen precipitates acute respiratory symptoms in asthmatic children.
    • Regular acetaminophen use does not appear to exacerbate asthma more than ibuprofen.

    Conclusions:

    • Single-dose acetaminophen administration is considered safe for children with a history of asthma.
    • Further prospective studies are needed to definitively confirm the association between acetaminophen and asthma development.
    • Clinicians can consider acetaminophen for short-term fever or pain relief in asthmatic children.