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Treatment of Venous Thromboembolism in Pediatric Patients

Lynn Malec1, Guy Young2

  • 1BloodCenter of Wisconsin, Milwaukee, WI, USA; Medical College of Wisconsin, Milwaukee, WI, USA.

Frontiers in Pediatrics
|March 16, 2017
PubMed

Insights

Pediatric venous thromboembolism (VTE) is rising. This review details treatment goals, options, and adverse events for anticoagulant therapy in children.

Area of Science:

  • Pediatric Hematology
  • Thrombosis Medicine
  • Clinical Pediatrics

Background:

  • Increasing incidence of venous thromboembolism (VTE) in pediatric populations.
  • Association of VTE with improved survival in medically complex children.
  • Rise in invasive supportive measures contributing to VTE risk.

Purpose of the Study:

  • To review current treatment goals for pediatric VTE.
  • To outline available anticoagulant treatment options for children.
  • To discuss adverse events related to anticoagulant use in pediatric VTE.

Main Methods:

  • Mini-review of existing literature on pediatric VTE.
  • Synthesis of information on treatment strategies and outcomes.
  • Analysis of safety profiles of anticoagulants in children.

Main Results:

  • Established treatment goals for pediatric VTE.
  • Overview of anticoagulant pharmacotherapy and administration in children.
  • Identification of common and serious adverse events.

Conclusions:

  • Effective management of pediatric VTE requires understanding specific treatment nuances.
  • Anticoagulant therapy in children necessitates careful consideration of risks and benefits.
  • Further research may refine optimal anticoagulant strategies for pediatric VTE.

Keywords:
anticoagulantspediatricsthromboembolismtreatmentvenous thrombosis

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