Genes for human vitamin K-dependent plasma proteins C and S are located on chromosomes 2 and 3, respectively

¹Department of Biochemistry, College of Medicine, University of Vermont, Burlington 05405.

|January 1, 1988

Abstract:

cDNAs encoding human proteins C and S have been used to screen a panel of mouse-human somatic cell hybrids to determine the chromosomal location of their respective genes. The gene for human protein C is located on chromosome 2, whereas that for protein S is located on chromosome 3. Analysis of human genomic DNA restriction endonuclease fragmentation patterns suggests that the human protein S gene is greater than 40 kb in size and contains a minimum of 11 introns.

Related Concept Videos

Articles linked to this work by shared authors, journal, and citation graph.

First Energy-Scan Measurement of e^{+}e^{-}→K^{+}K^{-} around the ψ(2S) Resonance.

Physical review letters·2026

First Experimental Constraint on the Scalar Current in the D^{0(+)}→K[over ¯]ℓ^{+}ν_{ℓ} Transition.

Physical review letters·2026

Measurements of the Absolute Branching Fraction of the Semileptonic Decay Ξ^{-}→Λe^{-}ν[over ¯]_{e} and the Axial Charge of Ξ^{-}.

Physical review letters·2026

First Observation of D^{0(+)}→K[over ¯]ωe^{+}ν_{e} and Determination of the Branching Fraction of K[over ¯]_{1}(1270)→K[over ¯]ω.

Physical review letters·2026

Measurement of the Λ electric dipole moment with an entangled baryon-antibaryon system.

Science (New York, N.Y.)·2026

First Measurement of the Absolute Branching Fraction of η_{c}→γγ.

Physical review letters·2026

See all related articles

Related Experiment Videos

Genes for human vitamin K-dependent plasma proteins C and S are located on chromosomes 2 and 3, respectively

Related Concept Videos

First Energy-Scan Measurement of e^{+}e^{-}→K^{+}K^{-} around the ψ(2S) Resonance.

First Experimental Constraint on the Scalar Current in the D^{0(+)}→K[over ¯]ℓ^{+}ν_{ℓ} Transition.

Measurements of the Absolute Branching Fraction of the Semileptonic Decay Ξ^{-}→Λe^{-}ν[over ¯]_{e} and the Axial Charge of Ξ^{-}.

First Observation of D^{0(+)}→K[over ¯]ωe^{+}ν_{e} and Determination of the Branching Fraction of K[over ¯]_{1}(1270)→K[over ¯]ω.

Measurement of the Λ electric dipole moment with an entangled baryon-antibaryon system.

First Measurement of the Absolute Branching Fraction of η_{c}→γγ.

Role of nuclear background and in vivo environment in variable segregation behavior of the aging-dependent T414G mutation at critical control site for human fibroblast mtDNA replication.

Polycation-mediated transfection: how to overcome undesirable side effects of sticky DNA complexes.

Chemically induced premature chromosome condensation in human fibroblast cell lines: fundamental study for applications to the biodosimetry of local exposure.

Removal of UV photoproducts from an adenovirus-encoded reporter gene following infection of unirradiated and UV-irradiated human fibroblasts.

Damage-repair kinetics and early adaptive response induced by gamma rays in murine leukocytes in vivo.

Defective NF-kappaB signaling in dedifferentiated hepatoma cells.

Solvent-Free Plasma-Assisted Synthesis of Hydroxyapatite Nanoparticles: Preparation, Characterization and Incorporation into Alginate Hydrogels.

Proton-gated multisite concerted proton-electron transfer-like pathway in a dual-atom framework for selective water purification.

Metastable C-Mo-O/Ni sites mediate partial oxidation of methane via O* species-assisted C-H bond activation pathway.

Determination of argon metastable densities in an electrosurgical argon plasma by TDLAS.

Effects of cordycepin on antioxidant capacity and proliferative potential of buffalo spermatogonial cells in vitro.

A reactant coordinate-based method with a goniometer-shaped grid: higher-order split operators and application to the resonance-mediated Cl + H2 (v = 1) reaction.

Related Experiment Videos

Genes for human vitamin K-dependent plasma proteins C and S are located on chromosomes 2 and 3, respectively

Abstract:

Related Concept Videos

Related Articles