Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antihypertensive Drugs: Vasodilators01:23

Antihypertensive Drugs: Vasodilators

2.4K
Vasodilators, primarily affecting the smooth muscles within arterial and venous walls, are commonly used for hypertension treatment. Medications such as minoxidil and hydralazine primarily target arteries and arterioles, while sodium nitroprusside acts on arterioles and venules. Minoxidil, functioning as a prodrug, is metabolized by hepatic sulfotransferase into its active form, minoxidil sulfate, after oral administration. This metabolite binds to the sulfonylurea receptor (SUR) component of...
2.4K
Multipotency and Niche of Bulge Stem Cell01:06

Multipotency and Niche of Bulge Stem Cell

4.3K
A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
4.3K
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

1.1K
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
1.1K
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors01:28

Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors

664
Phosphodiesterase 5 (PDE5) inhibitors are potent enzymes that function to hydrolyze cyclic nucleotides to their corresponding 5' monophosphates. Their unique biochemical properties have been applied in treating Pulmonary Arterial Hypertension (PAH).
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
664
Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

815
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
815

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quality by design-based development of transferrin-functionalized nanostructured lipid carriers for targeted Co-delivery of ropinirole and mangiferin for improved drug-delivery to the brain.

International journal of biological macromolecules·2026
Same author

The evolving landscape of osteoarthritis management: From conventional pharmacotherapy to gene therapy, stem cell therapy and nanotechnology-based therapeutics.

Nanomedicine : nanotechnology, biology, and medicine·2026
Same author

Metabolic-endocrine correlates of gut-brain axis mediators in polycystic ovary syndrome: A case-control study.

Journal of neuroendocrinology·2026
Same author

Retraction notice to ""2-(4-Fluorobenzamido)-4-methylthiazole-5-carboxylic acid" a novel thiazole compound, ameliorates insulin sensitivity and hyperlipidaemia in streptozotocin-induced diabetic rats: Plausible role of inflammatory and oxidative stress markers" [Biomedicine & Pharmacotherapy, 95 (2017) 1232-1241].

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026
Same author

Leprosy-tuberculosis co-infection: A case series.

Indian journal of dermatology, venereology and leprology·2026
Same author

STING and VDAC inhibitors attenuate inflammation and ineffective erythropoiesis caused by an altered metabolome in the <i>Nan</i> (EKLF/E339D) mouse model of neonatal anemia.

bioRxiv : the preprint server for biology·2025

Related Experiment Video

Updated: Mar 6, 2026

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
03:22

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia

Published on: January 27, 2018

15.7K

Dutasteride in Androgenetic Alopecia: An Update.

Tasleem Arif1, Konchok Dorjay2, Mohammad Adil2

  • 1Department of Dermatology, STDs and Leprosy, Jawaharlal Nehru Medical College (JNMC), Aligarh Muslim University (AMU), Aligarh, India, Al-Rahman Apartment, ground floor, Behind Zakaria market, New Sir Syed Nagar, Civil lines Aligarh. India.

Current Clinical Pharmacology
|March 16, 2017
PubMed
Summary

Dutasteride is an effective treatment for androgenetic alopecia, showing better results than finasteride with similar side effects. It may become a preferred option for hair loss treatment.

Keywords:
5-α-reductaseAndrogenetic alopeciadihydrotestosteronedutasteridefinasterideminoxidiltestosterone

More Related Videos

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
06:41

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis

Published on: March 9, 2015

9.5K
Murine Prostate Micro-dissection and Surgical Castration
08:49

Murine Prostate Micro-dissection and Surgical Castration

Published on: May 11, 2016

47.9K

Related Experiment Videos

Last Updated: Mar 6, 2026

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
03:22

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia

Published on: January 27, 2018

15.7K
A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
06:41

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis

Published on: March 9, 2015

9.5K
Murine Prostate Micro-dissection and Surgical Castration
08:49

Murine Prostate Micro-dissection and Surgical Castration

Published on: May 11, 2016

47.9K

Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Androgenetic alopecia involves scalp hair thinning due to testosterone conversion to dihydrotestosterone.
  • Dutasteride inhibits 5-α-reductase isoenzymes, targeting this pathogenesis.

Purpose of the Study:

  • To review the current status of dutasteride for androgenetic alopecia.
  • To compare dutasteride's efficacy and side effects with finasteride.

Main Methods:

  • Literature search using Medline, Pubmed, Google Scholar, and Scopus.
  • Keywords: 'dutasteride', 'dutasteride in androgenetic alopecia'.

Main Results:

  • Dutasteride demonstrates effectiveness in randomized controlled trials for androgenetic alopecia.
  • Studies indicate dutasteride is more effective than finasteride with comparable adverse effects.

Conclusions:

  • Dutasteride is a popular and effective treatment option for androgenetic alopecia.
  • Dutasteride may become a leading treatment choice for androgenetic alopecia in the future.