Variability in Antifungal and Antiviral Use in Hospitalized Children

Jennifer L Goldman1, Rachael K Ross2, Brian R Lee1

  • 11Children's Mercy Hospitals & Clinic,Kansas City,Missouri.

Insights

Antifungal and antiviral prescribing varied significantly among high-risk children in children

Area of Science:

  • Pediatric Infectious Diseases
  • Antimicrobial Stewardship
  • Hospital Epidemiology

Background:

  • High-risk children often require antifungal and antiviral medications.
  • Optimizing the use of these agents is crucial for patient outcomes and cost-effectiveness.

Purpose of the Study:

  • To analyze antifungal and antiviral prescribing patterns in high-risk children.
  • To identify variations in prescribing practices across freestanding children's hospitals.

Main Methods:

  • Retrospective analysis of prescribing data.
  • Comparison of antifungal and antiviral days of therapy across institutions.

Main Results:

  • Significant variation in antifungal and antiviral days of therapy was observed among children's hospitals.
  • No standardized approach to prescribing these agents was evident.

Conclusions:

  • Benchmarking antifungal and antiviral use is necessary.
  • Development of antimicrobial stewardship strategies is needed to optimize the use of these high-cost medications.

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