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Carbapenem-Resistant Enterobacteriaceae: A Strategic Roadmap for Infection Control
N Deborah Friedman1, Yehuda Carmeli2, Aaron Lea Walton1
11Barwon Health,Victoria,Australia.
Infection Control and Hospital Epidemiology
|March 16, 2017
Summary
Carbapenem-resistant Enterobacteriaceae (CRE) are a growing global threat with high mortality. Early detection and infection control are key to preventing widespread CRE epidemics.
Area of Science:
- Infectious Diseases
- Microbiology
- Public Health
Background:
- Rising global incidence of carbapenem-resistant Enterobacteriaceae (CRE) presents significant regional variations.
- CRE infections are associated with high crude mortality rates, up to 70%.
- The spread of CRE in healthcare settings constitutes a major medical and public health challenge.
Purpose of the Study:
- To provide a strategic roadmap for infection control measures against CRE.
- To enable the preparation of a multifaceted preparedness plan to prevent CRE epidemics.
- To outline proactive and adequate preventive measures at local, regional, and national levels.
Main Methods:
- Guideline development based on the best available evidence.
- Incorporation of expert opinion for strategic planning.
- Focus on early detection and comprehensive infection control.
Main Results:
- Highlights the critical need for a global preparedness plan for CRE.
- Identifies early detection via targeted laboratory protocols as crucial.
- Emphasizes containment of spread through robust infection control measures.
Conclusions:
- Preventing CRE endemicity requires a coordinated approach.
- Multifaceted preparedness plans are essential to avert CRE epidemics.
- Targeted laboratory detection and stringent infection control are paramount for success.
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