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A lysosome targetable fluorescent probe for endogenous imaging of hydrogen peroxide in living cells
Shahi Imam Reja1, Muskan Gupta2, Neha Gupta1
1Department of Chemistry, UGC Sponsored Centre for Advanced Studies-II, Guru Nanak Dev University, Amritsar, Punjab, India. mksharmaa@yahoo.co.in.
Abstract:
A lysosome targetable naphthalimide based fluorescent probe (LyNC) has been designed and synthesized which detects hydrogen peroxide (H2O2) with high selectivity and sensitivity in brain tissues and in living nematodes among various ROS/RNS tested. Further, the probe LyNC was successfully employed in exogenous and endogenous imaging of H2O2 in living cell lines.

