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Updated: Mar 6, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
[Complications After Transcatheter Aortic Valve Implantation]
A A Margolina1, K A Gruzdev1, M G Lepilin1
1Russian Cardiology Research and Production Complex, Moscow, Russia.
Transcatheter aortic valve implantation (TAVI) has a manageable complication rate. Bleeding and cardiac rhythm disturbances were most common, with no significant differences between TAVI approaches.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Transcatheter aortic valve implantation (TAVI) is a minimally invasive procedure for aortic stenosis.
- Assessing TAVI complication rates is crucial for patient safety and procedural optimization.
Purpose of the Study:
- To evaluate the incidence and types of complications following transcatheter aortic valve implantation (TAVI).
Main Methods:
- Retrospective analysis of 99 patients who underwent TAVI.
- Complications were categorized and compared between transapical and transfemoral TAVI approaches.
- Anesthesia types (general vs. local) were compared for specific complication rates.
Main Results:
- The most frequent complications included bleeding (17.2%), new cardiac rhythm disturbances requiring pacemakers (15.1%), and delirium (10.7%).
- Other complications observed were hemopericardium (6%), acute kidney injury (8.0%), stroke (7%), ventricular fibrillation (5.1%), and myocardial infarction (2%).
- No significant differences in complication rates were found between transapical and transfemoral TAVI. Ventricular fibrillation was more common with local anesthesia during transfemoral TAVI.
Conclusions:
- TAVI is associated with a spectrum of complications, predominantly bleeding and arrhythmias.
- Procedural approach (transapical vs. transfemoral) did not influence overall complication rates.
- Local anesthesia in transfemoral TAVI may increase the risk of ventricular fibrillation.
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