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[Arterial Hypertension and Optimization of Medication Prevention of Ischemic Stroke]

A V Fonyakin1, L A Geraskina1

  • 1Research Center of Neurology, Moscow, Russia.

Kardiologiia
|March 16, 2017
PubMed

Insights

Preventing stroke in arterial hypertension (AH) is crucial. Fixed-combination polypills improve adherence and effectiveness for stroke prevention in AH patients.

Area of Science:

  • Cardiovascular Medicine
  • Neurology
  • Pharmacology

Background:

  • Arterial hypertension (AH) is a major risk factor for stroke.
  • Cerebral complications of AH necessitate effective prevention strategies.

Purpose of the Study:

  • To outline the mechanisms of cerebral complications in AH.
  • To present key areas for stroke prevention in hypertensive patients.

Main Methods:

  • Review of large randomized trials.
  • Analysis of fixed-combination products (polypills).

Main Results:

  • Polypills combining antihypertensive and lipid-lowering drugs are justified.
  • These combinations improve treatment adherence.

Conclusions:

  • Fixed-combination polypills represent a key strategy for effective pharmacological stroke prevention in AH.
  • Improved adherence leads to enhanced effectiveness in preventing stroke.

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