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Updated: Mar 6, 2026

Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model
Published on: November 29, 2024
[Relationship Between Respiratory Function and Myocardial Structure and Function in Patients With Type 2 Diabetes
E D Bazdyrev1, Yu V Bayrakova1, O M Polikutina1
1FSBI Research Institute for Complex Issues of Cardiovascular Diseases, Siberian Branch of the Russian Academy of Medical Sciences, Sosnovy boul., 6, 650012 Kemerovo, Russia.
Purpose:
to analyze main parameters of respiratory dysfunction in patients with type 2 diabetes mellitus (DM) with and without concomitant ischemic heart disease (IHD).
Material And Methods:
We examined 104 patients with DM without (n= 64, 61.5%) and with (n=40, 38.5%) concomitant IHD. Examination included taking medical history, registration of parameters of myocardial and respiratory function and lung diffusion capacity. Resuts. Respiratory dysfunction in patients with DM was related to disease duration and glycose level. Presence of IHD and chronic heart failure of high functional class was associated with more pronounced reduction of forced expiratory volume in 1 sec and lung diffusion capacity.
Conclusion:
Revealed association between respiratory parameters and characteristics of the state of myocardium evidence for possible contribution of the latter in development of respiratory dysfunction in patients with DM.
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