[The Use of Novel Technologies for Assessment of Myocardial Function in Clinical Practice]

Key factors defining the prognosis of patients with heart failure (HF) are cardiac remodeling and myocardial contractility. New methods of visualization of myocardial motion gave impulse to research in the area of heart physiology and pathology. However in clinical practice these methods are still rarely used. Evaluation of systolic and diastolic functions based on tissue Doppler (TD), 2D and 3D speckle tracking data provides information on the pressure of left ventricular (LV) filling and enables carrying out differential diagnosis between constrictive pericarditis and myocardial diseases with diastolic dysfunction, dyspnea caused by cardiac and extracardiac causes. It also helps to understand physiology of systolic and diastolic dysfunction, impairment of LV pump function. It also enables monitoring response to HF treatment. Myocardial function analysis gives an opportunity to carry out early diagnostics, to detect subclinical LV dysfunction, to detect dyssynchrony and to predict response to resynchronising therapy. In this article we sum up indicators of systolic and diastolic dysfunction in various types of pathology and present assessment of mechanical dyssynchrony with the aid of TD, 2D and 3D speckle tracking. It is stressed that these methods allow carrying out quantitative analysis of myocardial motion. Practically all analyzed parameters are nonspecific and similar to parameters of remodeling change unidirectionally irrespective of pathology. The aim of this article is to summarize available data and knowledge on the determination of myocardial function. This is important for clinical practice and understanding of future development of the above methods.