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Updated: Mar 6, 2026

Herbal Munziq Ameliorates Myocardial Ischemia-Reperfusion Injury by Inhibiting Inflammation
Published on: January 10, 2025
[Myocardial Infarction and Natural Defense Mechanisms: The Role of Norepinephrine Reuptake]
S E Naumenko1, T V Latysheva1, M A Gilinsky1
1Scientific Research Institute of Physiology and Basic Medicine, Novosibirsk, Russia.
Purpose:
to study effect of norepinephrine reuptake blockade in reperfusion period on size of infarct caused by local ischemia with and without ischemic pre- and postconditioning.
Material And Methods:
Wistar rats (n=46) were randomly divided into 6 groups. Group (gr) I (n=7) - 30 min occlusion of left coronary artery followed by 120 reperfusion; gr II (n=2) as in gr I +desipramine (0.8 mg/kg intravenously [i.v.]) at the start of reperfusion; gr III (n=6) - ischemic preconditioning before coronary artery occlusion; gr IV (n=7).
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