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Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
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Macrophage Cholesterol Depletion and Its Effect on the Phagocytosis of Cryptococcus neoformans
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Cutaneous phaeohyphomycosis.

Mariana P Caviedes1, Ana C Torre1, Maite Lisa Eliceche1

  • 1Department of Dermatology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.

International Journal of Dermatology
|March 16, 2017
PubMed
Summary
This summary is machine-generated.

Phaeohyphomycosis, a fungal infection, is increasingly seen in immunocompromised individuals. Early recognition by dermatologists is crucial for diagnosis and treatment of these diverse cutaneous presentations.

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Area of Science:

  • Mycology
  • Dermatology
  • Infectious Diseases

Background:

  • Phaeohyphomycosis is a rare fungal infection with increasing prevalence in immunosuppressed patients, particularly solid organ transplant recipients.
  • The infection can manifest as mucocutaneous or disseminated disease, with cutaneous forms often resulting from direct fungal inoculation through trauma.
  • Cutaneous lesions are variable, can be asymptomatic, and typically appear on exposed areas like limbs and head.

Observation:

  • This report details three cases of phaeohyphomycosis presenting with cutaneous involvement.
  • The presented cases exhibit a range of clinical features, severity, and disease progression.

Findings:

  • The clinical diversity and variable evolution of phaeohyphomycosis underscore the challenges in diagnosis and management.
  • Successful diagnosis relies on high clinical suspicion to prompt appropriate microscopic examination and mycological culture.

Implications:

  • Dermatologists must be vigilant in recognizing phaeohyphomycosis due to its varied clinical presentations.
  • Prompt diagnosis through microscopy and culture, guided by clinical suspicion, is essential for effective management of this emerging fungal infection.