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Norfloxacin resistance in a clinical isolate of Escherichia coli
Antimicrobial Agents and Chemotherapy
|October 1, 1987
Abstract:
Analysis of DNA gyrase supercoiling and of norfloxacin uptake in Escherichia coli GN14176, a moderately norfloxacin-resistant clinical isolate, indicated that resistance was associated with both an altered drug target and a reduction in drug uptake.
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