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Updated: Mar 6, 2026
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MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
Published on: December 13, 2017
15.0K
Diffusion tractography imaging-guided frameless linear accelerator stereotactic radiosurgical thalamotomy for tremor:
Won Kim1, Justin Sharim2, Stephen Tenn3
1Departments of1Neurosurgery.
Journal of Neurosurgery
|March 17, 2017
Summary
This study introduces frameless linear accelerator (LINAC)-based thalamotomy, a novel approach for treating tremor. Diffusion tensor imaging (DTI) guided the precise targeting of the ventral intermediate (VIM) nucleus, leading to significant tremor reduction in a Parkinson's disease patient.
Area of Science:
- Neurosurgery
- Neurology
- Radiosurgery
Background:
- Essential tremor and Parkinson's disease-associated tremor are prevalent movement disorders.
- The ventral intermediate (VIM) nucleus of the thalamus is a common target for tremor treatment using deep brain stimulation and Gamma Knife radiosurgery.
- Existing literature extensively covers surgical planning and outcomes for these established methodologies.
Keywords:
AC = anterior commissureADL = activity of daily livingDBS = deep brain stimulationDTI = diffusion tensor imagingGKRS = Gamma Knife radiosurgeryLINACLINAC = linear acceleratorPC = posterior commissureParkinson's diseaseSRS = stereotactic radiosurgeryVIM = ventral intermediate nucleusdiffusion tractographyfunctional neurosurgerystereotactic neurosurgerytremor
