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Related Concept Videos

Unit Cells01:18

Unit Cells

34
A crystal's internal structure is an orderly array of atoms, ions, or molecules, and the details of this array significantly influence the solid's properties. In a crystal, periodically repeating 'structural motifs' - which could be atoms, molecules, or groups thereof - create a 'space lattice.' This is essentially a three-dimensional, infinite array of points, each surrounded by its neighbors in an identical way, forming the basic structure of the crystal.A 'unit cell' is a theoretical...
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Structures of Solids02:22

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Solids in which the atoms, ions, or molecules are arranged in a definite repeating pattern are known as crystalline solids. Metals and ionic compounds typically form ordered, crystalline solids. A crystalline solid has a precise melting temperature because each atom or molecule of the same type is held in place with the same forces or energy. Amorphous solids or non-crystalline solids (or, sometimes, glasses) which lack an ordered internal structure and are randomly arranged. Substances that...
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CELLS IN THE THIRD DIMENSION.

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    Explore advanced 3-D cell culture technologies, including hydrogels and organs-on-a-chip. These innovations are revolutionizing biological research and drug development.

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    Area of Science:

    • Biotechnology
    • Tissue Engineering
    • Cell Biology

    Background:

    • The evolution of 3-D cell culture models offers enhanced physiological relevance compared to traditional 2-D methods.
    • Advancements in biomaterials and microfabrication are driving innovation in creating complex cellular environments.

    Discussion:

    • Hydrogels provide tunable matrices for cell growth and differentiation, mimicking the extracellular matrix.
    • Microfluidic devices, or organs-on-a-chip, enable the study of organ-level functions and drug responses in vitro.

    Key Insights:

    • 3-D cell culture systems provide more accurate models for studying cellular behavior and disease mechanisms.
    • The integration of multiple cell types and vascularization in 3-D cultures is crucial for developing functional tissue models.

    Outlook:

    • Future developments aim to increase the complexity and scale of 3-D cultures, potentially leading to fully functional artificial organs.
    • These technologies hold significant promise for personalized medicine, drug screening, and regenerative therapies.