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Deaths Associated with Ankylosing Spondylitis in France from 1969 to 2009
Clément Prati1,2, Marc Puyraveau3,4, Xavier Guillot3,4
1From the Department of Rheumatology, CHU Besançon; FDE EA4267, (FHU INCREASE) Université de Bourgogne Franche-Comté; Centre de Méthodologie Clinique, CHU Besançon; EA 4266 Agents pathogènes et inflammation, Université de Bourgogne Franche-Comté, Besançon, France. praticlement@gmail.com.
Objective:
To describe deaths for which ankylosing spondylitis (AS) was on death certificates in France.
Methods:
Death certificates in which AS was indicated were evaluated. Standard mortality ratio (SMR) was assessed.
Results:
AS appeared in 2940 death certificates. The mortality rate of AS seemed stable. The most frequent initial causes were diseases of the circulatory system [28.3% in the International Classification of Diseases, 10th ed (ICD-10)]. SMR adjusted for age and sex were 2.1 (95% CI 1.45-2.91) for infections and 0.43 (0.36-0.5) for cancers (ICD-10 period).
Conclusion:
This study found an increase in mortality from infectious and external causes of death; conversely, patients with AS appear to die less frequently from cancer.
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