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Current Situation of Medication Adherence in Hypertension

Bernard Vrijens1, Sotiris Antoniou2, Michel Burnier3

  • 1WestRock HealthcareVisé, Belgium; Department of Public Health, University of LiègeLiège, Belgium.

Frontiers in Pharmacology
|March 17, 2017
PubMed

Insights

Poor adherence to hypertension treatments is a global issue, increasing cardiovascular risks. Simplifying medication regimens, like using single-pill combinations, can significantly improve patient adherence and blood pressure control.

Area of Science:

  • Cardiology
  • Public Health
  • Pharmacology

Background:

  • Poor medication adherence is a persistent global challenge in chronic disease management.
  • Antihypertensive therapy adherence issues are linked to higher risks of coronary and cerebrovascular events.
  • Despite improved hypertension control trends, a constant number of patients remain above goal, incurring personal and economic costs.

Purpose of the Study:

  • To present expert discussions on the current state of medication adherence in hypertension.
  • To highlight challenges and potential solutions for improving adherence in hypertensive patients.
  • To address the multifaceted nature of medication adherence, including initiation, implementation, and persistence.

Main Methods:

  • Review of current literature and expert opinion on medication adherence measurement.
  • Discussion of adherence barriers, including pill burden from complex antihypertensive regimens.
  • Evaluation of strategies to improve adherence, such as single-pill fixed-dose combinations and medication re-packing.

Main Results:

  • Medication adherence is a complex issue with distinct components: initiation, implementation, and persistence.
  • Accurate adherence measurement involves methods like electronic monitoring and drug level assays.
  • Simplifying medication regimens through single-pill combinations and re-packing shows promise for enhancing adherence.

Conclusions:

  • Addressing medication adherence is crucial for improving outcomes in hypertension management.
  • Strategies that reduce pill burden, such as fixed-dose combinations, are vital for enhancing patient adherence.
  • Continued expert dialogue and implementation of adherence-improving strategies are necessary to overcome this global health problem.

Keywords:
adherenceantihypertensiveimplementationinitiationmedicationpersistence

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