Related Experiment Video
Updated: Mar 6, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
Medication Adherence Among Elderly Patients with High Blood Pressure in Gweru, Zimbabwe
Elizabeth Wariva1, James January1, Julita Maradzika1
1Department of Community Medicine, College of Health Sciences, University of Zimbabwe , Harare, Zimbabwe.
Insights
Medication adherence in hypertensive patients is crucial for managing high blood pressure. Factors like patient knowledge and provider relationships significantly influence adherence, suggesting a need to focus on behavioral and educational interventions.
Area of Science:
- Public Health
- Cardiovascular Medicine
- Health Behavior
Background:
- High blood pressure (hypertension) is a significant global health issue.
- Effective management relies on anti-hypertensive medications.
- Medication adherence presents a major challenge for hypertensive patients worldwide.
Purpose of the Study:
- To assess predisposing, enabling, and reinforcing factors influencing medication adherence.
- Focus on hypertensive patients aged 40-70 years in Gweru urban.
- Identify key determinants of treatment compliance in this demographic.
Main Methods:
- Descriptive cross-sectional study design.
- Convenient sampling of 110 hypertensive patients.
- Interviewer-administered questionnaire based on the PRECEDE model (Phase 4).
Main Results:
- Significant associations found between medication adherence and age (P=0.0059), marital status (P=0.015), monthly income (P=0.0002), support groups (P=0.027), and patient knowledge (P=0.0058).
- Modal age was 70 years; mean age was 58 years (SD=10.29).
- Females constituted 61.8% and males 38.2% of the sample.
Conclusions:
- Enhancing patient knowledge and fostering strong patient-provider relationships are vital for improving medication adherence.
- Interventions should prioritize modifiable factors like predisposing, enabling, and reinforcing elements.
- Demographic and socio-economic factors, while associated, may be less amenable to change compared to behavioral and educational interventions.
Abstract:
High blood pressure is a global health concern which is mainly managed by taking anti-hypertensive medications. Although medication is available to control high blood pressure, adhering to treatment is a major problem among hypertensive patients. The purpose of the study was to assess the predisposing, enabling and reinforcing factors to medication adherence among hypertensive patients in Gweru urban aged 40-70 years. A descriptive cross sectional study was used with a sample size of 110 conveniently sampled hypertensive patients. We used an interviewer administered questionnaire designed using phase 4 of the PRECEDE model. The modal age was 70 years and mean age was 58 years (SD=10.29). There were 61.8% females and 38.2% males. Variables associated with medication adherence were: age (P=0.0059), marital status (P=0.015), average monthly income (P=0.0002), support group (P=0.027) and knowledge (P=0.0058). Providing information to patients with high blood pressure and having a good patient-provider relationship improves medication adherence. There is need to focus on the predisposing, enabling and reinforcing factors of medication adherence since demographic and socio-economic factors may be more difficult to change.
Related Concept Videos
Drug Dosing: Geriatric Patients
Hypertension V: Nursing Management
Hypertension IV: Drug Therapy and Lifestyle Modifications
Pharmacodynamics in Geriatric Patients: Effects of Age
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion