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Related Experiment Video

Updated: Mar 6, 2026

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

Aptamers: Biomedical Interest and Applications.

Cristina Romero-López¹, Alfredo Berzal-Herranz¹

¹Instituto de Parasitología y Biomedicina "López-Neyra", (IPBLN-CSIC), 18016 Armilla, Granada, Spain. Cristina_romero@ipb.csic.es.

Pharmaceuticals (Basel, Switzerland)

|March 17, 2017

Summary

Aptamers are DNA or RNA molecules that bind targets specifically. Developed through Systematic Evolution of Ligands by Exponential enrichment (SELEX), they offer potential for diagnostics and therapeutics.

Area of Science:

Biotechnology
Molecular Biology
Biochemistry

Background:

Keywords:

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Last Updated: Mar 6, 2026

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Aptamers are nucleic acid-based ligands with high specificity and affinity for target molecules.

The SELEX (Systematic Evolution of Ligands by Exponential enrichment) method was developed in 1990 for aptamer discovery.

Aptamers can be generated against a wide range of targets, including small molecules, proteins, and viruses.