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Updated: Mar 6, 2026

Characterization of In Vitro Differentiation of Human Primary Keratinocytes by RNA-Seq Analysis
Published on: May 16, 2020
Porokeratosis ptychotropica
Ana Carolina Franco Tebet1, Tatiana Gandolfi de Oliveira1, Anna Rita Ferrante Mitidieri de Oliveira1
1Universidade de Santo Amaro (UNISA) - Santo Amaro (SP), Brazil.
Abstract:
Porokeratosis is a skin disorder clinically characterized by annular plaques with keratotic borders resembling the Great Wall of China and histopathologically by cornoid lamellae. The disease has several clinical variants. Porokeratosis ptychotropica, which has recently become part of these variants, is quite rare and little known. The entity is characterized by verrucous plaques - which may resemble a psoriasis plaque - that affect the regions of the buttocks, most commonly the gluteal cleft, with or without extremity involvement. Itching is often present. We report a rare case of porokeratosis ptychotropica and highlight its unusual manifestation (single plaque), the first case reported in the Brazilian literature.
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