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Updated: Mar 6, 2026

Single-molecule Super-resolution Imaging of Phosphatidylinositol 4,5-bisphosphate in the Plasma Membrane with Novel Fluorescent Probes
07:26

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Published on: October 15, 2016

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PI5P and PI(3,5)P2: Minor, but Essential Phosphoinositides

Junya Hasegawa1, Bethany S Strunk1, Lois S Weisman1

  • 1Life Sciences Institute, University of Michigan.

Cell Structure and Function
|March 18, 2017
PubMed
Summary

Phosphatidylinositol 5-phosphate (PI5P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) are vital for cellular functions like endocytosis and stress adaptation. Defects in their biosynthesis are linked to neurodegenerative diseases, highlighting their pathophysiological importance.

Keywords:
EndocytosisFab1/PIKfyveMembrane traffickingPhosphoinositidesVacuoles/Lysosomes

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