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Relationship between functional endoscopy and impedance-pH measurement.

F Michel1,2, T Stroh3,4, R Fritsche3,4

  • 1Refluxcenter Darmstadt, Darmstadt, Germany. ohrweh@me.com.

HNO
|March 18, 2017
PubMed
Summary

Functional endoscopy (VPE) shows promise for diagnosing extra-esophageal reflux symptoms, correlating well with impedance-pH monitoring results. This aids in identifying the link between reflux and symptoms.

Keywords:
Esophageal pH monitoringExtra-esophageal refluxFunctional endoscopyLaryngitisTransnasal esophagoscopy

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Area of Science:

  • Gastroenterology
  • Diagnostic Medicine
  • Reflux Disease Research

Background:

  • Traditional diagnostic tools struggle to link extra-esophageal symptoms with pathological reflux.
  • Functional endoscopy, specifically video panendoscopy (VPE), is a potential new method.
  • Objective data on VPE's success in reflux diagnostics are lacking.

Purpose of the Study:

  • To investigate the relationship between endoscopic findings from VPE and impedance-pH monitoring in patients with extra-esophageal reflux symptoms.
  • To objectively verify the diagnostic utility of VPE in this patient group.

Main Methods:

  • Video panendoscopy (VPE) was performed on patients with extra-esophageal reflux symptoms.
  • Impedance-pH monitoring, the gold standard for esophageal reflux diagnostics, was conducted.
  • Correlation analysis between VPE findings and impedance-pH parameters was performed.

Main Results:

  • Pathological findings during VPE demonstrated a significant correlation with key impedance-pH monitoring parameters.
  • Specifically, correlations were observed with the number of reflux episodes, fraction time, and DeMeester score.
  • This supports the utility of VPE in assessing reflux activity.

Conclusions:

  • Video panendoscopy (VPE) findings correlate objectively with impedance-pH monitoring results in patients experiencing extra-esophageal reflux symptoms.
  • VPE appears to be a valuable tool for diagnosing the causal relationship between reflux and these symptoms.
  • Further validation of VPE in reflux diagnostics is supported by these findings.