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Global eradication of measles: Are we poised?
Raghavendra D Kulkarni1, G S Ajantha1, Aithal R Kiran2
1Department of Microbiology, SDM College of Medical Sciences and Hospital, Dharwad, Karnataka, India.
Abstract:
Measles, a highly infectious viral disease is the next target for eradication following poliovirus. Decades of experience with highly effective vaccination has invigorated us to take on this virus. The task is not only Titanic but is laced with intricate issues. Recently, an outbreak of fever with rash occurred on a tertiary care teaching hospital campus and was confirmed serologically as measles outbreak by IgMELISA. Therefore, we searched the literature related to outbreaks, transmission of the measles virus, age groups involved, vaccination strategies, vaccination failure and epidemiological features of the disease and reviewed the possible reasons for such outbreaks and problems in the global eradication of the virus.
Insights
Measles outbreaks remain a challenge despite effective vaccines. This study reviews measles transmission, vaccination failures, and epidemiological factors hindering global eradication efforts.
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- Measles is a highly infectious viral disease targeted for global eradication.
- Effective vaccination strategies have been developed over decades.
- Recent measles outbreaks highlight ongoing challenges.
Purpose of the Study:
- To review literature on measles outbreaks and global eradication challenges.
- To analyze transmission, affected age groups, and vaccination strategies.
- To identify reasons for outbreaks and obstacles to eradication.
Main Methods:
- Literature search on measles outbreaks, transmission, and epidemiology.
- Review of vaccination strategies and failure mechanisms.
- Analysis of epidemiological features and eradication challenges.
Main Results:
- Measles outbreaks continue to occur despite vaccination efforts.
- Vaccination failure and complex epidemiological factors contribute to outbreaks.
- Global eradication faces significant logistical and public health challenges.
Conclusions:
- Achieving global measles eradication requires addressing vaccination failures and complex transmission dynamics.
- Understanding epidemiological features is crucial for targeted interventions.
- Continued research and robust public health strategies are essential.
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