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Related Concept Videos

Endoscopic Procedures III: Video Capsule Endoscopy01:28

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Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers,...
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Related Experiment Video

Updated: Mar 6, 2026

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model
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The second-generation eCLIPs Endovascular Clip System: initial experience.

Albert H Chiu1,2,3, Joost De Vries4, Cian J O'Kelly5

  • 11Neurovascular Program.

Journal of Neurosurgery
|March 18, 2017
PubMed
Summary

The second-generation eCLIPs device offers a viable treatment for wide-necked bifurcation aneurysms, showing comparable occlusion rates to other devices. This endovascular clip system demonstrates effectiveness in complex intracranial aneurysm treatment.

Keywords:
ICA = internal carotid arteryMCA = middle cerebral arteryMRRC = modified Raymond-Roy ClassificationPCA = posterior cerebral arteryWEB = Woven EndoBridge Aneurysm Embolization Systembifurcation aneurysmembolizationflow diversioninterventional neuroradiologyinterventional neurosurgeryintracranial aneurysmradiologytherapeuticvascular disorders

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Area of Science:

  • Neurosurgery
  • Interventional Neuroradiology
  • Medical Devices

Background:

  • Treatment of wide-necked intracranial aneurysms, especially at bifurcations, presents challenges with existing methods.
  • High recanalization and complication rates are associated with current treatments for these complex aneurysms.

Purpose of the Study:

  • To evaluate the evolution, safety, and efficacy of the second-generation eCLIPs (Endovascular Clip System) device for treating bifurcation aneurysms.
  • To assess the device's performance in terms of deployment, complication rates, and long-term angiographic and clinical outcomes.

Main Methods:

  • A registry study involving 13 international centers treated patients with the second-generation eCLIPs device.
  • Data collected included aneurysm characteristics, procedural details, device coverage, coil retention, and patient follow-up (imaging and clinical).
  • Follow-up assessed angiographic results using the modified Raymond-Roy Classification and need for re-treatment.

Main Results:

  • Successful eCLIPs device placement was achieved in 76% of 33 treated patients, with a learning curve observed in early deployment.
  • Low rates of periprocedural complications were noted, including transient ischemic attacks and asymptomatic thrombotic events.
  • At an average 8-month follow-up, 81% of patients achieved a modified Raymond-Roy Classification of I or II, with 42.9% showing improvement in Raymond grade.

Conclusions:

  • The second-generation eCLIPs device is a feasible treatment option for intracranial bifurcation aneurysms.
  • Aneurysm occlusion rates achieved with eCLIPs are comparable to other bifurcation support devices in initial clinical series.
  • The device shows promise for managing complex wide-necked aneurysms, particularly at bifurcation sites.