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Dissection and Immunostaining of Imaginal Discs from Drosophila melanogaster
Published on: September 20, 2014
The expression of PS integrins in Drosophila melanogaster imaginal disc cell lines
David John Peel1, Martin John Milner1
1Department of Biology and Preclinical Medicine, Bute Medical Buildings, University of St. Andrews, St. Andrews, Fife, KY16 9TS, Scotland, UK.
Abstract:
Drosophila imaginal disc cell lines show a characteristic pattern of aggregation in culture, which appears to be due to cell-cell rather than cell-substrate interactions. We have examined the distribution of PS integrins in wing and leg cell lines, and find that these integrin homologues are expressed preferentially in aggregates. Cell sheets, small cell clumps and chains of cells express antigen at points of cell-cell contact only.

