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Pregnancy and delivery in a woman with severe haemophilia A

Jelena N Bodrozic1, Predrag S Miljic, Danijela R Lekovic

  • 1aClinic of Haematology, Clinical Center of Serbia bMedical Faculty, University of Belgrade cClinic for Obstetrics and Gynaecology, Clinical Center of Serbia, Belgrade, Serbia.

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis
|March 18, 2017
PubMed

: Severe form of haemophilia in women is an extremely rare condition. Owing to the rarity of the disease there are no precise recommendations concerning the optimal management of pregnancy and delivery in these patients. We are reporting the clinical course and management of a 30-year-old woman with a severe form of haemophilia A (factor VIII <1 IU/dl) during her first pregnancy and delivery. Antepartum, she was treated on demand by FVIII concentrate and she delivered at 37 weeks of gestation by cesarean section. In postpartal period an excellent control of bleeding was obtained by regularly administering FVIII concentrate for several days as well by concomitant use of tranexamic acid and oral contraceptive pills in the next 6 weeks.

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